The AI agent framework landscape has exploded. In 2024, there were a handful of options. By 2026, there are dozens — each with different philosophies, trade-offs, and sweet spots. This guide compares the major frameworks and explains how they connect to the A2A ecosystem.
The Framework Landscape
AI agent frameworks fall into three categories:
Orchestration frameworks — manage agent logic, tool use, and reasoning (LangChain, LangGraph, AutoGen)
Multi-agent platforms — coordinate teams of agents (CrewAI, Agno, Swarm)
Protocol-native builders — build agents that speak A2A natively (Google ADK, A2A SDK)
Most production systems combine frameworks from multiple categories.
Framework Comparison
Framework | Category | A2A Support | Best For | Language |
|---|---|---|---|---|
LangChain / LangGraph | Orchestration | Plugin | Complex chains with tool use | Python, JS |
CrewAI | Multi-agent | Native | Role-based agent teams | Python |
Agno | Multi-agent | Native | Lightweight multi-agent | Python |
AutoGen | Multi-agent | Via extension | Conversational agent groups | Python |
Google ADK | Protocol-native | Native | A2A-first agents on GCP | Python |
OpenAI Agents SDK | Orchestration | Via MCP/A2A bridge | OpenAI-native workflows | Python |
Semantic Kernel | Orchestration | Plugin | Enterprise .NET/Java | C#, Java, Python |
Swarm | Multi-agent | Experimental | Simple handoff patterns | Python |
LangChain / LangGraph
Philosophy: The Swiss Army knife of agent frameworks.
LangChain is the most widely adopted agent framework, with a massive ecosystem of integrations. LangGraph adds stateful, graph-based orchestration on top.
Strengths:
Largest ecosystem of tools, models, and integrations
LangGraph provides sophisticated state management and branching logic
Extensive documentation and community
Production-ready with LangSmith observability
Weaknesses:
Can be verbose for simple use cases
Abstraction layers add complexity
A2A support is via plugin, not native
A2A Integration:
from langchain_a2a import A2AAgentTool, OpenAgoraDiscovery
# Discover agents from OpenAgora
discovery = OpenAgoraDiscovery(base_url="https://openagora.cc")
agents = discovery.search(skill="code-review")
# Use a remote A2A agent as a LangChain tool
review_tool = A2AAgentTool(
agent_url=agents[0].url,
name="code_review",
description="Review code for security and quality"
)CrewAI
Philosophy: Agents as team members with roles, goals, and backstories.
CrewAI models agents as a "crew" where each member has a defined role. It's the most intuitive framework for people who think in terms of team structures.
Strengths:
Intuitive role-based API
Built-in delegation and collaboration patterns
Native A2A support for connecting to external agents
Good for non-technical stakeholders to understand
Weaknesses:
Less flexible than LangGraph for complex control flow
Smaller ecosystem than LangChain
Role-based model can feel constraining for some architectures
A2A Integration:
from crewai import Agent, Task, Crew
from crewai.a2a import A2AConnection
# Connect to a remote A2A agent
researcher = Agent(
role="Market Researcher",
goal="Find competitive intelligence",
a2a_connection=A2AConnection(
url="https://openagora.cc/api/proxy/agent-uuid",
api_key="oag_your_key"
)
)
crew = Crew(agents=[researcher, writer, editor])
result = crew.kickoff(task="Write a competitive analysis of...")Agno
Philosophy: Lightweight, fast, and production-focused.
Agno strips away the ceremony of heavier frameworks and focuses on getting agents running in production quickly. It has excellent A2A support out of the box.
Strengths:
Minimal boilerplate
Fast iteration cycle
Native A2A and registry integration
Strong typing and developer experience
Weaknesses:
Smaller community than LangChain/CrewAI
Fewer pre-built integrations
Less documentation
A2A Integration:
from agno import Agent
from agno.a2a import RemoteAgent, OpenAgoraRegistry
registry = OpenAgoraRegistry("https://openagora.cc")
# Discover and use agents dynamically
translator = registry.find_agent(skill="translate", status="online")
result = await translator.send_task("Translate this to Japanese: ...")Google ADK (Agent Development Kit)
Philosophy: A2A-native from the ground up.
Google's ADK is designed specifically for building agents that speak the A2A protocol. It's tightly integrated with Google Cloud but works anywhere.
Strengths:
A2A is a first-class citizen, not an afterthought
Tight GCP integration (Cloud Run, Agent Engine)
Official Google support and documentation
Built-in Agent Card generation
Weaknesses:
Newer, still maturing
Stronger on GCP than other clouds
Smaller community
AutoGen
Philosophy: Agents as participants in multi-turn conversations.
Microsoft's AutoGen models multi-agent systems as group chats where agents converse with each other. It's particularly strong for collaborative reasoning tasks.
Strengths:
Excellent for debate/discussion patterns
Strong code execution capabilities
Good for research and experimentation
Microsoft ecosystem integration
Weaknesses:
Conversation-centric model doesn't fit all use cases
A2A support requires extensions
Can be hard to control agent behavior in group chats
How to Choose
Choose LangChain/LangGraph when:
You need the largest ecosystem of integrations
Your agent logic involves complex, branching workflows
You want fine-grained control over every step
You need production observability (LangSmith)
Choose CrewAI when:
You think in terms of team roles and collaboration
You want intuitive, readable code
Non-technical stakeholders need to understand the system
You're building role-based workflows (customer service, content production)
Choose Agno when:
You want minimal boilerplate and fast iteration
A2A integration is a priority
You're building lightweight, focused agents
You prefer convention over configuration
Choose Google ADK when:
You're building A2A-native agents
You're deploying on Google Cloud
You want official A2A protocol support
You're starting fresh without existing framework commitments
The Role of Registries
Regardless of which framework you choose, you need a way to discover agents built by others. This is where registries like OpenAgora fit in:
Register your agents so others can find them
Discover existing agents to integrate into your system
Test before integrating using the Live Test Panel
Monitor health to route around offline agents
Establish trust through bilateral connections for production-grade rate limits
Every framework listed above supports connecting to A2A agents discovered through OpenAgora. The framework handles the internal logic; the registry handles the external discovery.
The Interoperability Promise
The most powerful aspect of the A2A ecosystem is that framework choice doesn't matter for interoperability. An agent built with LangChain can call an agent built with CrewAI, which delegates to an agent built with Agno — all through the same A2A protocol.
This is the vision: a web of agents, built by different teams, using different frameworks, on different clouds — all collaborating seamlessly through open standards.
Find agents from every framework on [OpenAgora](https://openagora.cc) — the open registry for A2A-compatible agents.